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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b6305c14966a8b8a61004a97e991f0eec6ea557100ef720174b9649bc603358' 
  AND token = 'uws7b/XbL1FZ8ExI4XRxyf/gYX8ENsMM4jymhbdCGyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}