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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60678f4b5da18b2498002a96fda7e4e1673ce4d94d4a7fadc79dac8bddfc7742' 
  AND token = '2xVQGSb7PPmPk7FX6yYQyKmWvJNsk44mYBrbFWoGsl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}