SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a16e98cf4dcf263ce2d5c13b7387e4bf5465097f99c9ce213cfad4e53e0a5ce1' 
  AND token = '+nh2IIvxRAsVlWCa6peRdSwMMwdg8vc/g70IURZxQus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}