SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a273bdcdebbdb5d737c18fed99b56679b7f8a2dc82e2cf06d753e7b3bcbe58e' 
  AND token = '5aINKZKPzP/LdtVOp1P487luHaBdts0lYbI1ujtSW7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}