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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e699ec5e41d3237edb91da7614869261f6c344c73fa92d3c53b09df22edd9e4d' 
  AND token = 'pJ7NMc/F5CHuk7n14EEInRiQvh3mrw3nqJ/+MbHcVtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}