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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e53b7bf36a59eecf455450ab56a72b00091a5470ffaa58861b4f0700949d590' 
  AND token = '78CB3dTYN1Ttwzq4SgbMpngnwCc889VyxV88OhVq+h4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}