SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25abb6393f8b10d4711dd1e4a3c412933b398327e97b93c48439ac85a5473231' 
  AND token = 'MkZn0b+5V6OAvqhg8HruhCCBuqokne21DAtWP7EhZpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}