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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '701ec79d0eebaf1e79e0bd35d71544bdedc0e28c6858bc632ff72c8da0b74764' 
  AND token = '5KoQO3qovHawgJ8IGHYgMviiCB1fEtDL97h0qte4VhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}