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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28578a1d0f694c36e3ab361153d257e3ee9289024897d74bd87c7fb132e1c88f' 
  AND token = 'GrZdvUD6cXB2FZRv272tTPu3RR/NOU+McftU0+16KjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}