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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e4b283d00e2fbe13c5420b64d65ae15399c6d1eb57224adfaa0ea9de6676995' 
  AND token = 'cysHhX9qNkznX/iFXwPV6z9ko+Ppk5R3H1GiNl+k5dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}