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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3967e48806e80243a210c9fa7e87183d98fd1e91c96e4c41fc410acbed41cefa' 
  AND token = 'gtmtcgTWz2cbfMt9LSdQHobeJ5RiyntLdZ0lUs8Zaec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}