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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5900be62947c4a3b0acd2f06f4a067aa684580e2c4e5e7c5f98b9effcfe2e841' 
  AND token = 'WDlpXTZkfe34dEXNAJgfb/8UL1hzf8jtP/iXLYcyyDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}