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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e03b30788edd9d94c8b9e2299e1ed20b9e243166d3db93be9c3b76f36aacd6a' 
  AND token = 'zAQQ2WNsQWfc1QSfyrvH2CYG6YfZ2Xilu4zTshZVGuY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}