SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1989abe7c5773ff082d431e8351fd6b0f7fe9df0e06b6f034db7c20178c49d' 
  AND token = 'Fq56LjztJQU1hIzNmOSVvR2yTTJiJS9L40nCW7ya400=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}