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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6049ff95d5d70cacfbe151a58fd9f01fa55c5c4822fc4a550951769371fe19a6' 
  AND token = 'SDMCXCF/onDU2vhY7V5iVfUTCTcB7vhthjqu0gvqtz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}