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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59907d5cd230b055e77e2b801e9722da0a87d0c0e7fe4d28bbff11840cb02cf3' 
  AND token = '8WoznYHLGF4B72xTmZoCJoOyPaSoQq9qpKLjHQBis/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}