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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d42602a462bab4bb8b8be9c983cbc42bd0aaa5e0e5e982c3479bce451a7972b' 
  AND token = '/yw2jx9vUfZdaWKcVvEny5j1CTAAdR2N90TtsdVuOhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}