SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eeff8a590449b348b61758946c06c022e58a3578c3d20060b19b30a0c66dc4fe' 
  AND token = 'IUmPERnk7yfmoEVJrrjL5wfN9NjnnOqumQ/jCQ1SeWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}