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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9016db74a3172707c59e986c83247559278fe5c29d6d14b86c25fbe1326e7edd' 
  AND token = 'KsGi+NUhBIlguxt+/gmi1i2c8EdgA8Aypd8Mg7OzO/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}