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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14c46a240c3f7bbc23aee4d4b71f83083b39af85449200700c3f3b939912e95b' 
  AND token = '60P+6m9LxMHGg5Q18ShQJLPMOvfDQvAoQtKASxwcrFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}