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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c60714d18de2521afda478a7bd321ed491425979c08fa739f6bf21adf3e460c' 
  AND token = 'tV3VF+bwW0tZZJ4EMQ4Dr3LXaaTkrqtBD69BM0tb3Qw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}