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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8791a9389d18909bbb2d802e359d8245ed003f526847d02bc6c2b8f53d19b88c' 
  AND token = 'T/wapY5CHQCUnZAW915/c72M4uSE3UXLEaPZ3mD/3oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}