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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3143f6577e7a3521d52d88f358240e76445c97f73cb757167df6365cf520d7' 
  AND token = 'cAv8QvXMuXctgj+NdbE1avg0VseldNjDTvfcpX4ITbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}