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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f3662fae459b9551e39d8916a0e08c7ef00e6241040880ec13e438827fa72b1' 
  AND token = 'LUs1EX2qT+iDM6ohOX/YZOklydHvuBTiMqdWgi1zs38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}