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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c89f94396b266e68d3fbd821bdaa4fd39dc424f5a1641e179e215c65985de89e' 
  AND token = 'T1USeA7DycYe+jlhxs1TVTeHMUb3PQjMMTq00FKvyJs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}