SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45850fdbe53a0737a90688699a111633baae6816b23b52349483e30b2b49a07' 
  AND token = 'l60Sz+CFs2Goh1Pd2IDHCgtD/R3qLBrOl8/qk0mG1ns=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}