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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99181770140c7dcda7955503dd18d7e273617226a8ad2674ae371501125a84ca' 
  AND token = 'QxW1ElcQgJyYYUNSpv0tVmuj1Oe8Z1TWNmfuxnHix6o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}