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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451370f9c7b73f01a56ede87b2fbf0c19f03f973c83677d57b138625dabc71ad' 
  AND token = 'GEN6jp+3Frla4w85ZVkrTTffJKDIu6KCMCEzGNS/zk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}