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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61328e5e8da2ae73de4faa903f3d0659f7ae1848bf23390333145d901a3189ca' 
  AND token = 'DYTtiiVmf9pBDhUR+sOo71FRiPph8LXx+0c1AzXv30Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}