SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a066d682e9045e39f248c33c2d8f527b00f8e8cb3270c5948127fda7bca523d1' 
  AND token = 'w6K60V/G6s7X0/UXlvhLc3mbjKIwC/PumWXlZYXmSuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}