SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2808b30dd328b477e27d08cfb29c73003efd3f895e56248fb29da00f08a88c27' 
  AND token = 'DpXBt6cF0Q0LNoda0u41axWd2sA099oa3GMR/h3dvN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}