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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2246c7a0cd384b310a2ea1fc745cd9bb9ef007bd18eaca2df1c49b55b67bc1' 
  AND token = 'RuH9II3/pCOd6WUM0u3c//sx/6aXonGt1ABJew9aI6s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}