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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a5c35440b613a76ccd77fccbd71300f7f5a1a363e86904e04f232115511c49' 
  AND token = 'MdTdvEdnVqODVC7znDYRW6Y8EZR7Aw+Kc7If+tGQiBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}