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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81e692103d27d1a88e8673670aef0e240e9dbf6609dc848cdf0352950d0e3622' 
  AND token = '4AtvyId0N6PHVICqyjnrikvtZmLdQg2jq02aP7qfyu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}