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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3463a2fb37474b0e29ad70177b19a10e9492b8531d27e4935252788155fafba0' 
  AND token = 'lRd5TJH0S8KzP/PciWr4SeYlSW0S1o7FUckfWUhYbZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}