SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12d97bae819f43dfbbf0d15a156fd488935604598c38ba6f8a611b587a68d5a' 
  AND token = 'etVTpTr4IgJ56Khw7gDHuNKahCtlEAjC4oQ0UAir9NQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}