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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a589c3a0032dc52deb69e81834dfd1520b3f9a35d3ff6728029020deeb4e5d3' 
  AND token = 'uSfzLgdM8g6Y5+06GD933HdPR53eYM+2zS696MbDAls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}