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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a5c16f466a00198f49ec1940576e168daad716ac4ce92f3b1839fd038fbb7b9' 
  AND token = '0yJHWzKGvujVuarkA80DzvcsU9plvel+zZpScqDewAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}