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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bf23a702f96d59ae8e78c6d050f7b8b2378ee145bb068e18cbec4ef615f4e06' 
  AND token = '+ySo1IlVYRjNB4mY1b8tKI0E30kAQ8J1dGXPUJ7PRT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}