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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73be1edcbe2fe30f43fe6c939df1ed8fd833f2a9668d50c6cdfbc089442fc845' 
  AND token = '9Uf4WVdn6RQHH8UJdOFLntvFz+kFJxPi9WzaDJCb+Uo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}