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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cddf0b794e883dab8a523fd2efda8e2c4ffde1fd7251ba01efb0ce1e2e1aa082' 
  AND token = 'owPs1b27OcV8AL0XIxEnXh7XkezlrJyelEYAZZTTdwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}