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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1351697d863e313aa43fce25c64ae54a3b28b029b588020c79f89cb10d64caa4' 
  AND token = '+kYb1UH735v4E0qyx+PpyK0b31uLZ/cTVlCILqGWf3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}