SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '946e0362ff3bd11eeb58f78ec8767c45b63568645f0765af08c0127cddf6e009' 
  AND token = 'TNLm+x+CVfo0zL/Yucm9bgAHc8wn+z90FAg3hTsu6oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}