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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e4ea50e932ea42e4f0001ba706b69791ef3ab32d4c11aa6287bca721acdfe23' 
  AND token = 'fdulLZwmb1GNqYE0KWTiaFpcMmeAPhMYKwsqWQwR46A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}