SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca075bf5bbdffd6ccd2457118b7e68ac45fc922f5bfce070309bd9a035aaa763' 
  AND token = 'IHux+D5PUBCDi6n4y3DplqSTcUt6iUBM6mgcdGfzTv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}