SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75e253a7cd27289a3e969b9940849ca62bea0e09741e2a57b91bb8bf554cedea' 
  AND token = 'B0sEkhBuDuyTuKdI/40We2bRuDAu7RYOP00mB377JKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}