SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372e41a8fc98d99f405ec88a46a2dafd9b0cda162be4ccabf25c24f0dcee1cea' 
  AND token = 'l5msGMTTxwN7s+FI1Tyjf8QrcomY1Gzjk7+shndLaB4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}