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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6afc9aaf9e5a9782b972b6896b85818ab80f78b141301726852c29fe536519eb' 
  AND token = '44GR79VjpCzEzZHrf2SeGucPi0QGikRqW9xzZCEjKRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}