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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44c21f1da5d4d7ce56de3ad9f51bdc34ceeba836137d7d413e565e0d746a807' 
  AND token = 'OJmSTlI29KPMyieor38LWB5U14pZp1+vzSnIglwUqNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}