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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5df96968ebad85d07aea74f1302eaf3b8c2aec8d41bfcf60d167eda8a316a3b8' 
  AND token = 'PwPvey+mHO7P4veyC6/+B+BkEYIffWFnSIf6Gvv25Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}